Immunotherapy-Induced Acute Tubulointerstitial Nephritis

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Acute and Chronic Tubulointerstitial Nephritis

Cellular and fluid exudation in the interstitial tissue was noted by Councilman in 1898, while he studied kidneys of patients who died of scarlet fever and diphtheria (1). Councilman also determined that these kidneys did not contain bacteria (they were sterile). He called the condition acute interstitial nephritis (AIN). The term interstitial nephritis connotes predominant involvement of the r...

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Acute tubulointerstitial nephritis associated with celecoxib.

Four days later (after 3 weeks of complete anuria) diuresis started to resume. Urinalysis revealed proteinuria (4.12 g/24 h), lambda light chains (2.41 g/l) and microhaematuria. Subsequently, complement normalized and urinalysis became negative. Creatinine dropped to 106mmol/l and no paraprotein was detectable in neither serum nor urine. In conclusion, this report describes one of the oldest pa...

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Acute tubulointerstitial nephritis/drug induced acute kidney injury; an experience from a single center in Pakistan.

INTRODUCTION There is no information in literature specifically on the prevalence and clinicopathological characteristics of acute tubulointerstitial nephritis/drug induced acute kidney injury (AKI) from Pakistan. OBJECTIVES We aim to report a series of cases from patients developing AKI after exposure to some medications or finding of interstitial nephritis on histopathology. PATIENTS AND ...

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ژورنال

عنوان ژورنال: Cureus

سال: 2021

ISSN: 2168-8184

DOI: 10.7759/cureus.15358